High-fat diet during pregnancy makes new cells in fetal brain that cause early onset obesity.
A study in rats shows that laying open to a high-fat diet during pregnancy produces durable changes in the offspring’s brain that lead to overeating and obesity early in life, according to new delve into by Rockefeller University scientists.
This surprising finding, reported in the Nov. 12 issue of the Journal of Neuroscience , provides a key step toward understanding mechanisms of fetal programming involving the production of new brain cells that may help explain the increased prevalence of childhood obesity during the last 30 years.
“We’ve shown that short-term exposure to a high-fat diet in utero produces permanent neurons in the fetal brain that later increase the appetite for fat,” says senior author Sarah F. Leibowitz, who directs the Laboratory of Behavioral Neurobiology at Rockefeller. “This work provides the first evidence for a fetal program that links high levels of fats circulating in the mother’s blood during pregnancy to the overeating and increased weight gain of offspring after weaning.”
Research in adult animals by Leibowitz and others has shown that circulating triglycerides stimulate brain chemicals known as orexigenic peptides, which in turn spur the animals to eat more. Scientists also have shown that obese and diabetic mothers produce heavier children and that exposure to fat-rich foods early in life leads to obesity in adulthood. These studies suggested that food intake and body weight may be programmed during fetal development. But little was known about the mechanism underlying this programming.
Leibowitz and her colleagues have identified mechanisms in the brain that explain this programming. They looked at the effects of feeding pregnant rats a high fat diet for two weeks compared with a balanced diet containing a moderate amount of fat. The researchers found that rat pups born to mothers who consumed the high fat diet, even after the diet had been removed at birth, ate more, weighed more throughout life, and began puberty earlier than those born to mothers who ate a balanced diet for the same two week period. They also had higher levels of triglycerides in the blood at birth and as adults and greater production of brain peptides that stimulate eating and weight gain.
Leibowitz and her colleagues then looked at the pups’ brain development during the last week of pregnancy. They examined the number and types of neurons being born and made a surprising discovery: The pups from the mothers fed high fat diets had, in utero, a much larger number of neurons that produce the appetite-stimulating orexigenic peptides - and they kept them throughout their lives. During gestation, the mother’s fat-rich diet also stimulated the proliferation of neuronal precursor cells and their differentiation and migration to obesity-promoting centers in the brain. In rats on a balanced diet, these neurons were much fewer in number and appeared much later after birth.
“We believe the high levels of triglycerides that the fetuses are exposed to during pregnancy cause the growth of the neurons earlier and much more than is normal,” says Leibowitz.
The researchers hypothesize that because the mother must prepare her embryos to survive on her diet, they need to be born with the brain mechanisms that allow them to eat and metabolize it.
Leibowitz believes similar mechanisms may be operating in humans.
“We’re programming our children to be fat,” she says. “I think it’s very clear that there’s vulnerability in the developing brain, and we’ve identified the site of this action where new neurons are being born. We now need to understand how the lipids affect these precursor cells that form these fat-sensitive neurons that live with us throughout life.”
http://www.rockefeller.edu/
Parenting Seminar (free)
26/6 Sat
10am Admiralty Centre 2866 2028
2pm TseungKwanO Centre in Hang Hao 2191 0787
Bring along your friends
20.6.10
19.6.10
Autism and social deprivation
A neurodevelopmental disorder is defined as an impairment of the growth and development of the central nervous system. It effects the childs brain function in controlling emotion, learning ability and memory as well as social interaction. Today, one in six children is diagnosed with some forms of development and behaviour disorder. It is advised for parent to have their child diagnosed early, if they found that their child is withdrawing from social world, failing to learn the basic communication skill or struggle with emotional regulation, etc.. otherwise, a child may be at risk of becoming serious lifelong disability.
Autism
Autism is one most common form of brain development disorder and one in 166 child is diagnosed with some forms of autism. It is defined as medical condition in which a child has some of the following impairments
a) Speech
b) Social and communication skills
c) Limited interest
d) Repetitive behaviour
http://health.articlealbum.com/childrens-health-brain-development-disorder-definition-and-types/
As no specific cause for autism can be identified, we suspect that autism is in part due to acute deprivation of language stimulation during the critical period in the first year after birth.
Never leave your baby at home doing nothing when you and your husband go to work. Your child needs rich language environment and social interaction for his brain development.
Autism
Autism is one most common form of brain development disorder and one in 166 child is diagnosed with some forms of autism. It is defined as medical condition in which a child has some of the following impairments
a) Speech
b) Social and communication skills
c) Limited interest
d) Repetitive behaviour
http://health.articlealbum.com/childrens-health-brain-development-disorder-definition-and-types/
As no specific cause for autism can be identified, we suspect that autism is in part due to acute deprivation of language stimulation during the critical period in the first year after birth.
Never leave your baby at home doing nothing when you and your husband go to work. Your child needs rich language environment and social interaction for his brain development.
31.5.10
珍惜嬰幼期
周先生,
您好,我是由去年6 月開始支持你們的家長,我從事教育工作的,當時我的女兒只有6 月大,現在已17個月大了,我深信您那一套對幼兒語言教育的理念,並認為我的選擇是對的。
我最滿意的是日語老師(金鍾星期天),我和女兒上她的課簡直是一種享受,她很細心地安排每一個教學活動,互動性強,小朋友往往被她吸引着,對她我是讚不絕口的。另外是法語課(Remi & Raphael),他們亦能仔細地安排每一個教學活動,多元化的教學環節,還有網上重溫。
而在香港最着重的是兩文三語,我最重視的是英語,Belinda 的教學絕對是無可置疑,她很活躍,每一環節都激發幼兒思考,非常吸引,而每一環節都有連貫的...
後來就試了___的課,我認為他可在以下方面作出改善以提升教學質素:
1. 不要害羞,放大聲音,盡情享受與孩子玩樂。
2. 每一環節多點連貫,如 Belinda 那樣。
3. 多一點紀律和互動性,例如我之前提及Emily的優點,多鼓勵小孩說話。
4. 勿死板地拿着教具或字咭讀,要滲入在活動中教。
我去了其他地方試堂,相比之下,你們的課堂安排仍然是優秀的,東山的孩子真的比較機靈,簡直是天淵之別,所以我更加不能不提意見,而眼睜睜地看着質素高的東山退步!
你們的課堂在優秀的基礎上再做得更好是我們家長的福份,靜候您的佳音,望老師方面有所改善,如果Emily 老師能回來則更理想,加價也值。
Ron 媽,
非常感謝您的寶貴意見,我們會知會有關的老師,並在明天早上的會議進行討論。
容我也給您提一個小小的意見,17個月的孩子,還是在語言學習和腦部發展的高峰期。孩子每天需要大量營養,支持身體的成長,更需要豐富的語言環境,及和其他小朋友的相處,刺激腦部的發育和語言的成長,隔天才提供良好的環境,並不足夠。高峰期到兩歲半左右,告一段落。
珍惜這段寶貴的高速學習期,安排在你要上班的日子,每天都讓孩子到中心參加活動,擴闊對不同文化、不同語言的接觸面,拉闊音域,培養自信心和領袖才,發揮孩子的語言天份。錢是可以賺回來的,孩子的高速學習期,一去不複返。
歡迎出週六家長研討會
6月5日(星期六)
上午10至11時半 尖沙咀漢口道17號新聲大廈6樓 電話:2376 1808
下午2至3時半 金鐘海富中心一座5樓 電話:2866 2028
6月12日(星期六)
上午10至11時半 金鐘海富中心一座5樓 電話:2866 2028
下午2至3時半 坑口安寧花園商場後座 電話:2191 0787
您好,我是由去年6 月開始支持你們的家長,我從事教育工作的,當時我的女兒只有6 月大,現在已17個月大了,我深信您那一套對幼兒語言教育的理念,並認為我的選擇是對的。
我最滿意的是日語老師(金鍾星期天),我和女兒上她的課簡直是一種享受,她很細心地安排每一個教學活動,互動性強,小朋友往往被她吸引着,對她我是讚不絕口的。另外是法語課(Remi & Raphael),他們亦能仔細地安排每一個教學活動,多元化的教學環節,還有網上重溫。
而在香港最着重的是兩文三語,我最重視的是英語,Belinda 的教學絕對是無可置疑,她很活躍,每一環節都激發幼兒思考,非常吸引,而每一環節都有連貫的...
後來就試了___的課,我認為他可在以下方面作出改善以提升教學質素:
1. 不要害羞,放大聲音,盡情享受與孩子玩樂。
2. 每一環節多點連貫,如 Belinda 那樣。
3. 多一點紀律和互動性,例如我之前提及Emily的優點,多鼓勵小孩說話。
4. 勿死板地拿着教具或字咭讀,要滲入在活動中教。
我去了其他地方試堂,相比之下,你們的課堂安排仍然是優秀的,東山的孩子真的比較機靈,簡直是天淵之別,所以我更加不能不提意見,而眼睜睜地看着質素高的東山退步!
你們的課堂在優秀的基礎上再做得更好是我們家長的福份,靜候您的佳音,望老師方面有所改善,如果Emily 老師能回來則更理想,加價也值。
Ron 媽,
非常感謝您的寶貴意見,我們會知會有關的老師,並在明天早上的會議進行討論。
容我也給您提一個小小的意見,17個月的孩子,還是在語言學習和腦部發展的高峰期。孩子每天需要大量營養,支持身體的成長,更需要豐富的語言環境,及和其他小朋友的相處,刺激腦部的發育和語言的成長,隔天才提供良好的環境,並不足夠。高峰期到兩歲半左右,告一段落。
珍惜這段寶貴的高速學習期,安排在你要上班的日子,每天都讓孩子到中心參加活動,擴闊對不同文化、不同語言的接觸面,拉闊音域,培養自信心和領袖才,發揮孩子的語言天份。錢是可以賺回來的,孩子的高速學習期,一去不複返。
歡迎出週六家長研討會
6月5日(星期六)
上午10至11時半 尖沙咀漢口道17號新聲大廈6樓 電話:2376 1808
下午2至3時半 金鐘海富中心一座5樓 電話:2866 2028
6月12日(星期六)
上午10至11時半 金鐘海富中心一座5樓 電話:2866 2028
下午2至3時半 坑口安寧花園商場後座 電話:2191 0787
28.5.10
Introducing our Summer Program - (1) English Communication
When kids take over the classroom
‘I get more opportunities to speak in class.’
“It’s fun!” said Byeong-jun. “I have more opportunity to speak out in this small class. I usually don’t have that much of chance to speak English in regular class. There’s about 30 of us. But here I can ask all the questions I want. It’s cool to talk to my friends in English, too.”
“In a regular class, students sometimes hesitate to present their thoughts and answers in English because the class atmosphere is generally strict. But in this Saturday class, they are aggressive, in a good way, eager to jump in at any time because the class atmosphere encourages students not to be afraid of making mistakes.”
“There’s no special reason that we’re here,” Jin-yeong said. “It’s just because learning English is fun!”
http://joongangdaily.joins.com/article/view.asp?aid=2903260
This is exactly what we are going to do in English Communication in our summer program, run by trained native teachers. Let kids take over the classroom. Let them talk. Let them talk about the people they like, games they play, toys they love.
The role of teacher metamorphoses from a person who lectures into a facilitator and a resource person. The teacher becomes the host of a discussion program, introducing a hot topic of common interest, involving children and drawing out their ideas. The teacher becomes a resource person, helping participants to get the word one is looking for, repeating the word to make the pronunication right.
Is the outcome of the discussion important? Perhaps. It must mean quite a lot to the participants. But our key objective is to make learning English fun.
Our objective is to build up confidence and the verbal skills in communicating in English.
Share this with your friends. Tell us what you think.
[Don't miss our Gifted Babies Program for young babies and toddlers. They learn languages a hundred times faster than adults. Come to our Parenting Seminar Tel: 2866 2028]
‘I get more opportunities to speak in class.’
“It’s fun!” said Byeong-jun. “I have more opportunity to speak out in this small class. I usually don’t have that much of chance to speak English in regular class. There’s about 30 of us. But here I can ask all the questions I want. It’s cool to talk to my friends in English, too.”
“In a regular class, students sometimes hesitate to present their thoughts and answers in English because the class atmosphere is generally strict. But in this Saturday class, they are aggressive, in a good way, eager to jump in at any time because the class atmosphere encourages students not to be afraid of making mistakes.”
“There’s no special reason that we’re here,” Jin-yeong said. “It’s just because learning English is fun!”
http://joongangdaily.joins.com/article/view.asp?aid=2903260
This is exactly what we are going to do in English Communication in our summer program, run by trained native teachers. Let kids take over the classroom. Let them talk. Let them talk about the people they like, games they play, toys they love.
The role of teacher metamorphoses from a person who lectures into a facilitator and a resource person. The teacher becomes the host of a discussion program, introducing a hot topic of common interest, involving children and drawing out their ideas. The teacher becomes a resource person, helping participants to get the word one is looking for, repeating the word to make the pronunication right.
Is the outcome of the discussion important? Perhaps. It must mean quite a lot to the participants. But our key objective is to make learning English fun.
Our objective is to build up confidence and the verbal skills in communicating in English.
Share this with your friends. Tell us what you think.
[Don't miss our Gifted Babies Program for young babies and toddlers. They learn languages a hundred times faster than adults. Come to our Parenting Seminar Tel: 2866 2028]
27.5.10
The Developing Mind needs rich language environment and play
Young children know, feel and learn more than we ever imagined.
PERSONALITY & SOCIAL SKILLS (EQ) Recent discoveries indicate the important role social interaction plays in early learning and in later success in school and life.
COGNITION (IQ) Human cognition is complex and requires memory, problem-solving, logic, mathematical reasoning, and the manipulation of physical tools and abstract symbols.
LANGUAGE (LQ) Language is affected by a critical period. Skills not developed early are not easily corrected by later remediation attempts.
- Institute of Languages and Brain Sciences, Washington University, Seattle.
Early language training boosts IQ. University of North Carolina
http://www.fpg.unc.edu/~abc/FPG_ABC-video.cfm
Le Beaumont's Gifted Babies program offers a stimulating environment rich in culture and languages, to boost the EQ, IQ & LQ of infants and toddlers.
Find out more at Beaumont Parenting Seminar (Reservation requested)
Afternoon in Admiralty: 2:30 p.m. - 4:00 p.m. Tel: 2191 0787
PERSONALITY & SOCIAL SKILLS (EQ) Recent discoveries indicate the important role social interaction plays in early learning and in later success in school and life.
COGNITION (IQ) Human cognition is complex and requires memory, problem-solving, logic, mathematical reasoning, and the manipulation of physical tools and abstract symbols.
LANGUAGE (LQ) Language is affected by a critical period. Skills not developed early are not easily corrected by later remediation attempts.
- Institute of Languages and Brain Sciences, Washington University, Seattle.
Early language training boosts IQ. University of North Carolina
http://www.fpg.unc.edu/~abc/FPG_ABC-video.cfm
Le Beaumont's Gifted Babies program offers a stimulating environment rich in culture and languages, to boost the EQ, IQ & LQ of infants and toddlers.
Find out more at Beaumont Parenting Seminar (Reservation requested)
Afternoon in Admiralty: 2:30 p.m. - 4:00 p.m. Tel: 2191 0787
21.5.10
Hillary Clinton Addresses Early Childhood Nutrition
May 17, 2010
The following is excerpted from speech given by Secretary of State Hillary Clinton at the 2010 National CARE Conference. The statistics are daunting. For the full speech, go to http://www.state.gov/secretary/rm/2010/05/141726.htm.
“One in three children worldwide suffers from under-nutrition. In some countries, half of all children are stunted, which impedes their brain development and causes lifelong health and learning problems.
More than 3 million children and 100,000 mothers die every year from causes related to under-nutrition, which weakens immune systems, makes people susceptible to other health problems such as anemia, which is a leading contributor of maternal mortality, and pneumonia, which is the leading cause of death for children worldwide.
Under-nutrition impairs the effectiveness of life-saving medications, including the antiretrovirals needed by people living with HIV and AIDS. And the effects of under-nutrition linger for generations. Girls stunted by under-nutrition grow up to be women who are more likely to endure, if they survive, difficult pregnancies. And then their children, too, come into life undernourished.
So nutrition is a universal need and people of all ages and circumstances deserve access to nutritious foods. But the two groups that have the most acute need for improved nutrition are pregnant women and children, particularly babies. This is due in part to feeding practices that have women and children, particularly girls, eating last and eating least. But it also reflects the particular health needs of women, especially mothers and especially young children.
Nutrition plays the most critical role in a person’s life during a narrow window of time – the 1,000 days that begin at the start of a pregnancy and continue through the second year of life. The quality of nutrition during those 1,000 days can help determine whether a mother and child survive pregnancy and whether a child will contract a common childhood disease, experience enough brain development to go to school and hold a job as an adult.
The science of nutrition points to a strategy. If we target that brief critical period during which nutrition has the biggest impact and focus on improving nutrition for expectant mothers, new mothers, and young children, we can accomplish several things at once. We can save lives, we can help children start life on a better path, and we can bolster economic development and learning down the road.”
Sam Chow, Director of the Gifted Babies Program in Le Beaumont Language Centre, who has invested 10,000 hours in the R & D on early brain development and language acquisition, has the following observation. "The first 1,000 days after birth are indeed critical to child development. In developing countries, the problem is with the lack of nutrition. In developed countries, the problem is with the lack of language stimulation and social interaction. One in every 6 children in UK has language development problems.
Don't leave your baby at home. Don't let your baby grow up under acute deprivation of language stimulation and social interaction during the critical first 1,000 days because both parents are away at work. Join the Gifted Babies program and let your baby grow up into a gifted child in a multi-lingual multi-cultural environment rich in stimulation and social interaction.
The following is excerpted from speech given by Secretary of State Hillary Clinton at the 2010 National CARE Conference. The statistics are daunting. For the full speech, go to http://www.state.gov/secretary/rm/2010/05/141726.htm.
“One in three children worldwide suffers from under-nutrition. In some countries, half of all children are stunted, which impedes their brain development and causes lifelong health and learning problems.
More than 3 million children and 100,000 mothers die every year from causes related to under-nutrition, which weakens immune systems, makes people susceptible to other health problems such as anemia, which is a leading contributor of maternal mortality, and pneumonia, which is the leading cause of death for children worldwide.
Under-nutrition impairs the effectiveness of life-saving medications, including the antiretrovirals needed by people living with HIV and AIDS. And the effects of under-nutrition linger for generations. Girls stunted by under-nutrition grow up to be women who are more likely to endure, if they survive, difficult pregnancies. And then their children, too, come into life undernourished.
So nutrition is a universal need and people of all ages and circumstances deserve access to nutritious foods. But the two groups that have the most acute need for improved nutrition are pregnant women and children, particularly babies. This is due in part to feeding practices that have women and children, particularly girls, eating last and eating least. But it also reflects the particular health needs of women, especially mothers and especially young children.
Nutrition plays the most critical role in a person’s life during a narrow window of time – the 1,000 days that begin at the start of a pregnancy and continue through the second year of life. The quality of nutrition during those 1,000 days can help determine whether a mother and child survive pregnancy and whether a child will contract a common childhood disease, experience enough brain development to go to school and hold a job as an adult.
The science of nutrition points to a strategy. If we target that brief critical period during which nutrition has the biggest impact and focus on improving nutrition for expectant mothers, new mothers, and young children, we can accomplish several things at once. We can save lives, we can help children start life on a better path, and we can bolster economic development and learning down the road.”
Sam Chow, Director of the Gifted Babies Program in Le Beaumont Language Centre, who has invested 10,000 hours in the R & D on early brain development and language acquisition, has the following observation. "The first 1,000 days after birth are indeed critical to child development. In developing countries, the problem is with the lack of nutrition. In developed countries, the problem is with the lack of language stimulation and social interaction. One in every 6 children in UK has language development problems.
Don't leave your baby at home. Don't let your baby grow up under acute deprivation of language stimulation and social interaction during the critical first 1,000 days because both parents are away at work. Join the Gifted Babies program and let your baby grow up into a gifted child in a multi-lingual multi-cultural environment rich in stimulation and social interaction.
Brain Development
Brain development in a Preschooler Brain development commences in children as early as when they are babies. As per researches, early childhood care and experiences are believed to serve as an important prerequisite to a developing brain. It is also wise to reflect on the say, ’we are born with few traits and we acquire some’ in the process to become more informed and learned. A similar process works for our brains and intellect. Human brain is composed of a complex network of neurons that collect information and process it further to yield outputs. The more early these neural pathways are stimulated, the better it facilitates learning as one grows older.
http://blog.indianwomenshealth.com/brain-development/
http://blog.indianwomenshealth.com/brain-development/
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